Trial Profile

KB407-02 A Phase 1 Study of Inhaled KB407, a Replication-Defective, Non-Integrating Vector Expressing Human Cystic Fibrosis Transmembrane Conductance Regulator, for the Treatment of Cystic Fibrosis

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 26 May 2026

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At a glance

Drugs KB 407 (Primary)
Indications Cystic fibrosis
Focus Adverse reactions
Acronyms CORAL-1
Sponsors Krystal Biotech

Most Recent Events

07 May 2026 Planned number of patients changed from 12 to 20.
07 May 2026 Planned End Date changed from 1 Jun 2026 to 1 Mar 2027.
07 May 2026 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2026.

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