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KB407-02 A Phase 1 Study of Inhaled KB407, a Replication-Defective, Non-Integrating Vector Expressing Human Cystic Fibrosis Transmembrane Conductance Regulator, for the Treatment of Cystic Fibrosis

Trial Profile

KB407-02 A Phase 1 Study of Inhaled KB407, a Replication-Defective, Non-Integrating Vector Expressing Human Cystic Fibrosis Transmembrane Conductance Regulator, for the Treatment of Cystic Fibrosis

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 22 Jan 2026

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At a glance

  • Drugs KB 407 (Primary)
  • Indications Cystic fibrosis
  • Focus Adverse reactions
  • Acronyms CORAL-1
  • Sponsors Krystal Biotech

Most Recent Events

  • 09 Jan 2026 Interim results from Cohort 3 (data cut-off-January 6, 2026 ;n=7) presented at Krystal Biotech media release.
  • 08 Jan 2026 According to a Krystal Biotech media release, company will host an investor conference call and webcast tomorrow, Thursday, January 8, 2026, at 4:30 pm ET, to disclose an interim clinical update from CORAL-1.
  • 21 Aug 2025 Planned End Date changed from 1 Jul 2025 to 1 Jun 2026.

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