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A Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study Assessing Safety, Tolerability, Pharmacodynamics, Efficacy, and Pharmacokinetics of DYNE-251 Administered to Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study Assessing Safety, Tolerability, Pharmacodynamics, Efficacy, and Pharmacokinetics of DYNE-251 Administered to Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Sep 2026

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At a glance

  • Drugs Zeleciment rostudirsen (Primary)
  • Indications Duchenne muscular dystrophy
  • Focus Adverse reactions; First in man; Registrational; Therapeutic Use
  • Acronyms DELIVER
  • Sponsors Dyne Therapeutics

Most Recent Events

  • 08 Sep 2026 According to Dyne Therapeutics media release, data from this trial will be presented at the 31st Annual International Congress of the World Muscle Society (WMS) being held September 29, 2026, through October 3, 2026, virtually and in Hiroshima, Japan, as well as the 2026 Annual Meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) being held September 29, 2026, through October 2, 2026, virtually and in Orlando, Florida.
  • 11 Aug 2026 Planned End Date changed from 1 Nov 2029 to 1 Sep 2031.
  • 11 Aug 2026 Planned primary completion date changed from 1 Nov 2029 to 1 Sep 2031.

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