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A Phase I, Open-Label, Two-Part Study of the Effect of Multiple-Dose Evobrutinib on Transporter Substrates Digoxin, Metformin, Rosuvastatin, and Sumatriptan Pharmacokinetics in Healthy Participants

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Trial Profile

A Phase I, Open-Label, Two-Part Study of the Effect of Multiple-Dose Evobrutinib on Transporter Substrates Digoxin, Metformin, Rosuvastatin, and Sumatriptan Pharmacokinetics in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Jan 2022

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At a glance

  • Drugs Evobrutinib (Primary) ; Digoxin; Metformin; Rosuvastatin; Sumatriptan
  • Indications Encephalomyelitis; Multiple sclerosis
  • Focus Pharmacokinetics
  • Sponsors Merck KGaA

    • Most Recent Events

    • 10 Jan 2022 Status changed from recruiting to completed.
    • 10 Nov 2021 Status changed from not yet recruiting to recruiting.
    • 07 Oct 2021 New trial record

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