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A Phase 1, Open-label, Multi-part Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution, and CNS Signal of the Positron Emission Tomography Ligand 11C-BMS-986196 in Healthy Participants After Intravenous Administration and to Evaluate the Safety, Tolerability, Kinetics, and CNS Signal Repeatability of 11C-BMS-986196 After Repeat Intravenous Administration in Participants With Multiple Sclerosis

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Trial Profile

A Phase 1, Open-label, Multi-part Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution, and CNS Signal of the Positron Emission Tomography Ligand 11C-BMS-986196 in Healthy Participants After Intravenous Administration and to Evaluate the Safety, Tolerability, Kinetics, and CNS Signal Repeatability of 11C-BMS-986196 After Repeat Intravenous Administration in Participants With Multiple Sclerosis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 29 Mar 2024

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At a glance

  • Drugs BMS-986196 (Primary)
  • Indications Multiple sclerosis
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 26 Mar 2024 Status changed from recruiting to completed.
    • 16 Feb 2024 Planned End Date changed from 23 Jul 2023 to 30 Aug 2024.
    • 16 Feb 2024 Planned primary completion date changed from 23 Jul 2023 to 30 Aug 2024.

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