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The Effects of ATLAS (Arginine Tetrahydrobiopterin L-Ascorbate) Therapy on Nitric Oxide Bioavailability and Pain-free Walking in Patients With Intermittent Claudication

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Trial Profile

The Effects of ATLAS (Arginine Tetrahydrobiopterin L-Ascorbate) Therapy on Nitric Oxide Bioavailability and Pain-free Walking in Patients With Intermittent Claudication

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Apr 2026

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At a glance

  • Drugs Arginine (Primary) ; Ascorbic acid (Primary) ; Sapropterin (Primary)
  • Indications Intermittent claudication; Peripheral arterial disorders
  • Focus Pharmacokinetics
  • Acronyms ATLAS

Most Recent Events

  • 15 Apr 2026 Status changed from recruiting to active, no longer recruiting.
  • 06 Apr 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2027.
  • 06 Apr 2025 Planned primary completion date changed from 1 Jul 2025 to 1 Jul 2027.

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