A Phase 1/2a Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and/or Pharmacodynamics of ARO-C3 in Adult Healthy Volunteers and in Adult Patients With Complement-Mediated Renal Disease
Latest Information Update: 14 Aug 2024
At a glance
- Drugs ARO-C3 (Primary)
- Indications Autoimmune disorders; IgA nephropathy; Kidney disorders; Liver disorders; Membranoproliferative glomerulonephritis; Paroxysmal nocturnal haemoglobinuria
- Focus Adverse reactions
- Sponsors Arrowhead Pharmaceuticals
- 31 May 2024 According to an Arrowhead Pharmaceutical media release, results assessing the Safety, Tolerability, and Pharmacodynamics of ARO-C3, a Subcutaneously Administered Investigational RNA-interference Therapeutic Targeting Complement C3 in Adult Healthy Volunteers from this trial will be presented at the 22nd Asian Pacific Congress of Nephrology (APCN 2024) - June 13-16, 2024.
- 11 Apr 2024 Planned End Date changed from 1 Dec 2024 to 1 Jun 2025.
- 10 Nov 2023 Planned End Date changed from 1 Jun 2024 to 1 Dec 2024.