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A Prospective Phase II Clinical Study of Orelabrutinib in Combination With Lenalidomide and Rituximab (OLR) in First-line Treatment of Mantle Cell Lymphoma

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Trial Profile

A Prospective Phase II Clinical Study of Orelabrutinib in Combination With Lenalidomide and Rituximab (OLR) in First-line Treatment of Mantle Cell Lymphoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Sep 2024

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At a glance

  • Drugs Lenalidomide (Primary) ; Orelabrutinib (Primary) ; Rituximab (Primary)
  • Indications Mantle-cell lymphoma
  • Focus Therapeutic Use
  • Acronyms POLARIS
  • Most Recent Events

    • 14 Jun 2024 Results presented in an InnoCare Pharma Media Release.
    • 14 Jun 2024 According to an InnoCare Pharma media release, results from this trial were presented at the European Hematology Association (EHA) 2024 Hybrid Congress.
    • 12 Dec 2023 Preliminary Results (As of July 10, 2023, n=28) assessing efficacy, safety, and mutation spectrum of OLR regimen in untreated MCL presented at the 65th American Society of Hematology Annual Meeting and Exposition

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