Trial Profile

A Phase II Study of FOLFIRINOX Combined With the Glycogen Synthase Kinase-3 Beta (GSK-3 β) Inhibitor 9-ING-41 and the Transforming Growth Factor-β (TGF-β) Inhibitor Losartan in Patients With Untreated Metastatic Pancreatic Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 21 Aug 2026

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At a glance

Drugs Elraglusib (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Losartan (Primary) ; Oxaliplatin (Primary)
Indications Adenocarcinoma; Pancreatic cancer
Focus Therapeutic Use

13 Apr 2026 Planned End Date changed from 31 Jul 2026 to 31 Dec 2026.
13 Apr 2026 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2026.
25 Feb 2025 According to a Actuate Therapeutics media release, the company look forward to reporting final results from the trial in 2026

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