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A randomized exploratory open-label phase II study on the effect of durvalumab and tremelimumab combined with personalized SIRT (p-SIRT), standard-dose SIRT (sd-SIRT) or immunotherapy followed by on-demand loco-regional SIRT (od-SIRT) in non-resectable hepatocellular carcinoma (HCC) patients

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A randomized exploratory open-label phase II study on the effect of durvalumab and tremelimumab combined with personalized SIRT (p-SIRT), standard-dose SIRT (sd-SIRT) or immunotherapy followed by on-demand loco-regional SIRT (od-SIRT) in non-resectable hepatocellular carcinoma (HCC) patients

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Aug 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary)
  • Indications Liver cancer
  • Focus Therapeutic Use
  • Acronyms Zugspitze

    • Most Recent Events

    • 23 Mar 2022 Planned number of patients changed from 81 to 84.
    • 23 Mar 2022 Planned End Date changed from 14 Oct 2025 to 14 Oct 2024.
    • 20 Oct 2021 New trial record

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