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A Phase 1-2 Dose-escalation and Expansion Study of ST316 in Subjects With Selected Advanced Unresectable and Metastatic Solid Tumors

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Trial Profile

A Phase 1-2 Dose-escalation and Expansion Study of ST316 in Subjects With Selected Advanced Unresectable and Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 12 Jun 2024

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At a glance

  • Drugs ST 316 (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Cervical cancer; Cholangiocarcinoma; Colorectal cancer; Male breast cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Solid tumours; Synovial sarcoma; Triple negative breast cancer
  • Focus Adverse reactions; First in man; Proof of concept
  • Sponsors Sapience Therapeutics

    • Most Recent Events

    • 03 Jun 2024 Planned number of patients changed from 156 to 115.
    • 05 Mar 2024 According to a Sapience Therapeutics media release, following completion of the study's Phase 1 portion, the recommended dose will advance to the Phase 2 dose expansion portion of the study in colorectal cancer patients.
    • 13 Oct 2023 According to a Sapience Therapeutics media release, data from this trial presented in a poster presentation at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking place Oct 11-15, 2023, in Boston, MA.

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