A Phase IB Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Latest Information Update: 04 Jan 2025
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At a glance
- Drugs Mosunetuzumab (Primary) ; Tocilizumab
- Indications Chronic lymphocytic leukaemia
- Focus Adverse reactions
- Sponsors Roche
- 03 Dec 2024 Planned End Date changed from 8 Oct 2029 to 30 Oct 2029.
- 03 Dec 2024 Planned primary completion date changed from 27 May 2027 to 31 Aug 2027.
- 04 Dec 2023 Study design is changed from single-group assignment to parallel. Number of treatment arms increased from 1 to 3 by the addition of Arms B and C, where mosunetuzumab in combination with venetoclax is used in the regimen of arm C. Timeline for primary end-point for Arm-C is added as 24 months.