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A Randomized, Open Label, Multi-center, Active-comparator Study to Assess Efficacy, Safety & Tolerability of Ofatumumab 20mg sc Monthly Versus Continued Current Therapy in Relapsing-remitting Multiple Sclerosis After Elevation of Serum Neurofilament Light Levels (SOSTOS)

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Trial Profile

A Randomized, Open Label, Multi-center, Active-comparator Study to Assess Efficacy, Safety & Tolerability of Ofatumumab 20mg sc Monthly Versus Continued Current Therapy in Relapsing-remitting Multiple Sclerosis After Elevation of Serum Neurofilament Light Levels (SOSTOS)

Status: Active, no longer recruiting
Phase of Trial: Phase IV

Latest Information Update: 30 Jan 2026

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At a glance

  • Drugs Ofatumumab (Primary)
  • Indications Multiple sclerosis
  • Focus Therapeutic Use
  • Acronyms SOSTOS
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 17 Dec 2025 Planned End Date changed from 31 Dec 2026 to 1 Mar 2027.
  • 17 Dec 2025 Status changed from recruiting to active, no longer recruiting.
  • 09 Sep 2024 Planned End Date changed from 27 Jan 2027 to 31 Dec 2026.

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