Trial Profile

A Phase Ib/II Study of AK112PD-1 / VEGF Bispecific Antibody in Combination With AK117Anti-CD47 AntibodyWith or Without Chemotherapy in Advanced Malignant Tumors

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 06 Mar 2026

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At a glance

Drugs Ivonescimab (Primary) ; Ligufalimab (Primary)
Indications Adenocarcinoma; Biliary cancer; Cholangiocarcinoma; Gallbladder cancer; Gastrointestinal cancer; Non-small cell lung cancer; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions; Therapeutic Use
Sponsors Akeso Biopharma

Most Recent Events

03 Mar 2026 Status changed from active, no longer recruiting to completed.
12 Mar 2025 Planned End Date changed from 25 Jan 2025 to 1 Jun 2026.
12 Mar 2025 Planned primary completion date changed from 25 Aug 2024 to 1 May 2025.

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