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A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer, Whose Tumors Express PD-L1

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A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer, Whose Tumors Express PD-L1

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Aug 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Sacituzumab govitecan (Primary) ; Carboplatin; Gemcitabine; Paclitaxel
  • Indications Advanced breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ASCENT-04
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 13 Sep 2022 Trial design presented at the 47th European Society for Medical Oncology Congress.
    • 29 Aug 2022 According to a Gilead Sciences media release, data from this trial will be presented at the European Society for Medical Oncology (ESMO) Congress 2022.
    • 16 May 2022 Status changed from planning to recruiting.

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