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A multicenter, phase 2 study to evaluate safety and efficacy of panitumumab re-challenge based on circulating tumor DNA analysis in patients with RAS/BRAF V600E wild-type unresectable metastatic colorectal cancer with prior treatment history of anti-EGFR antibody

Trial Profile

A multicenter, phase 2 study to evaluate safety and efficacy of panitumumab re-challenge based on circulating tumor DNA analysis in patients with RAS/BRAF V600E wild-type unresectable metastatic colorectal cancer with prior treatment history of anti-EGFR antibody

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Oct 2024

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At a glance

  • Drugs Irinotecan (Primary) ; Panitumumab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms PURSUIT

Most Recent Events

  • 16 Oct 2024 Planned number of patients changed to 50.
  • 26 May 2022 According to an Amgen media release, results from this study will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting, 2022.
  • 02 Nov 2021 New trial record

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