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A Phase 2, Open-Label, Single-Arm Study of Single-Dose Lead-In and Neoadjuvant Trilaciclib and Chemotherapy in Patients With Early-Stage Triple Negative Breast Cancer (TNBC)

Trial Profile

A Phase 2, Open-Label, Single-Arm Study of Single-Dose Lead-In and Neoadjuvant Trilaciclib and Chemotherapy in Patients With Early-Stage Triple Negative Breast Cancer (TNBC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Mar 2024

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At a glance

  • Drugs Trilaciclib (Primary) ; Anthracyclines; Carboplatin; Cyclophosphamide; Doxorubicin; Paclitaxel; Pembrolizumab; Taxanes
  • Indications Carcinoma; Early breast cancer; Triple negative breast cancer
  • Focus Pharmacodynamics
  • Sponsors G1 Therapeutics

Most Recent Events

  • 08 Jan 2024 Results published in the G1 Therapeutics Media Release.
  • 06 Jun 2023 Results combining immune analysis with clinical outcomes to identify correlates of treatment response, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
  • 04 Jun 2023 According to a G1 Therapeutics media release, data from this study presented at the American Society of Clinical Oncology (ASCO) 2023 Annual Meeting

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