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A Phase 3, Randomized, Double-Blind Study of Pembrolizumab Versus Placebo in Combination With Paclitaxel With or Without Bevacizumab for the Treatment of Platinum-resistant Recurrent Ovarian Cancer (KEYNOTE-B96/ENGOT-ov65)

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Trial Profile

A Phase 3, Randomized, Double-Blind Study of Pembrolizumab Versus Placebo in Combination With Paclitaxel With or Without Bevacizumab for the Treatment of Platinum-resistant Recurrent Ovarian Cancer (KEYNOTE-B96/ENGOT-ov65)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Jul 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Docetaxel (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYNOTE-B96
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 15 May 2025 according to the Merck and Co Media Release. Results will be presented at an upcoming medical meeting and shared with regulatory authorities worldwide.
  • 15 May 2025 Primary endpoint (Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors 1.1 (RECIST 1.1) by Investigator) has been met, according to the Results published in the Merck and Co Media Release.
  • 15 May 2025 Results published in the Merck and Co Media Release.

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