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Antibody-Drug Conjugate Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Inhibitor Sequential GM-CSF and IL-2 for the Treatment Advanced Refractory Solid Tumors With HER-2 Positive(PRaG3.0)

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Trial Profile

Antibody-Drug Conjugate Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Inhibitor Sequential GM-CSF and IL-2 for the Treatment Advanced Refractory Solid Tumors With HER-2 Positive(PRaG3.0)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Jul 2023

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At a glance

  • Drugs Disitamab vedotin (Primary) ; Granulocyte macrophage colony stimulating factor
  • Indications Advanced breast cancer; Cervical cancer; Gastric cancer; Gynaecological cancer; Pancreatic cancer; Solid tumours
  • Focus Therapeutic Use
  • Acronyms PRaG3.0

    • Most Recent Events

    • 06 Jun 2023 Preliminary results (n=32) assessing efficacy and safety of PRaG3.0 regimen for therapy of HER2-expressing advanced solid tumors presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 05 Jun 2023 According to RemeGen Co., Ltd. media release, data from this trial were presented at 2023 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 2-6, 2023, in Chicago.
    • 07 Jun 2022 Status changed from not yet recruiting to recruiting, as per results presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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