Trial Profile

A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 27 Oct 2025

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At a glance

Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Pemetrexed (Primary) ; Sotorasib (Primary)
Indications Adenosquamous carcinoma; Non-small cell lung cancer
Focus Therapeutic Use

20 Oct 2025 Planned End Date changed from 20 Oct 2025 to 20 Oct 2027.
20 Oct 2025 Planned primary completion date changed from 20 Oct 2025 to 20 Oct 2027.
19 Sep 2023 Planned End Date changed from 20 Oct 2023 to 20 Oct 2025.

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