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A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Finding Study to Assess the Safety and Effectiveness of Tovinontrine in Patients With Chronic Heart Failure With Reduced Ejection Fraction

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Trial Profile

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Finding Study to Assess the Safety and Effectiveness of Tovinontrine in Patients With Chronic Heart Failure With Reduced Ejection Fraction

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Aug 2024

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At a glance

  • Drugs Tovinontrine (Primary)
  • Indications Heart failure
  • Focus Proof of concept; Therapeutic Use
  • Acronyms Cycle-1-REF
  • Sponsors Cardurion Pharmaceuticals; Enliven Therapeutics; Imara Inc
  • Most Recent Events

    • 16 Jul 2024 According to a Cardurion Pharmaceuticals media release, company announced it has raised a $260 million Series B financing led by Ascenta Capital and proceeds from the financing will be used to support later-stage clinical trials with the company's two lead drug candidates CRD-750 and CRD-4730.
    • 08 Mar 2024 Status changed from not yet recruiting to recruiting.
    • 23 Feb 2023 According to an Enliven Therapeutics media release, Imara Inc has merged with Enliven Therapeutics. The combined company will operate under the name, Enliven Therapeutics

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