An Open Label, Phase 1/1b Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Patients With Myelofibrosis
Latest Information Update: 21 Jan 2026
At a glance
- Drugs Imetelstat (Primary) ; Ruxolitinib (Primary)
- Indications Myelofibrosis
- Focus Adverse reactions; Therapeutic Use
- Acronyms IMproveMF
- Sponsors Geron Corporation
Most Recent Events
- 06 Jan 2026 Planned number of patients changed from 51 to 36.
- 08 Dec 2025 According to a Geron Corporation media release, data from this study presented at the 67th American Society of Hematology (ASH) 2025 Annual Meeting being held in Orlando, FL.
- 28 May 2025 According to Geron Corporation media release, company announced presentation of data from this study at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting and the European Hematology Association (EHA) 2025 Congress.