Trial Profile

Phase 1/2 Open Label Dose-escalation and Expansion Trial of NKT2152 an Orally Administered HIF2α Inhibitor to Investigate Safety Pharmacokinetics Pharmacodynamics and Clinical Activity in Patients With Advanced Clear Cell Renal Cell Carcinoma

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 17 Nov 2025

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At a glance

12 Nov 2025 Actual primary completion date is 22 August 2025
12 Nov 2025 Status changed from active, no longer recruiting to discontinued as a result of Sponsor portfolio reprioritization.
26 Oct 2025 Results (n=42) presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025

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