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Phase 1/2 Open Label Dose-escalation and Expansion Trial of NKT2152 an Orally Administered HIF2α Inhibitor to Investigate Safety Pharmacokinetics Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal Cell Carcinoma

Trial Profile

Phase 1/2 Open Label Dose-escalation and Expansion Trial of NKT2152 an Orally Administered HIF2α Inhibitor to Investigate Safety Pharmacokinetics Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal Cell Carcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Jan 2025

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At a glance

  • Drugs NKT 2152 (Primary)
  • Indications Renal cell carcinoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors NiKang Therapeutics

Most Recent Events

  • 16 Oct 2024 Status changed from recruiting to active, no longer recruiting.
  • 16 Oct 2024 Planned primary completion date changed from 1 Sep 2024 to 1 May 2025.
  • 09 Sep 2024 According to a NiKang Therapeutics media release, company announced that preliminary data from this study will be presented in an oral presentation at the European Society for Medical Oncology (ESMO) 2024 Congress on September 13, 2024, in Barcelona, Spain.

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