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A Phase I Open-Label, Dose Escalation Study of the Safety and Tolerability of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

Trial Profile

A Phase I Open-Label, Dose Escalation Study of the Safety and Tolerability of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Nov 2025

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At a glance

  • Drugs Tolododekin alfa (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Bladder cancer; Head and neck cancer; Lung cancer; Male breast cancer; Malignant melanoma; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Acronyms ANCHOR
  • Sponsors Ankyra Therapeutics

Most Recent Events

  • 04 Nov 2025 According to an Ankyra Therapeutics media release, company will be presenting initial data with their ANK-201 at the Society for Immunotherapy of Cancer annual meeting on November 7, 2025.
  • 04 Nov 2025 According to an Ankyra Therapeutics media release, company recently completed dose escalation in this study.
  • 04 Nov 2025 According to an Ankyra Therapeutics media release, company announced the publication online of Part 1 results from its Phase 1 first-in-human study of tolododekin alfa in Nature Communications in the September 29, 2025, issue.

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