A Phase 2a Study to Type I-Polarized Autologous Dendritic Cell Vaccines Incorporating Tumor Blood Vessel Antigen (TBVA)-Derived Peptides in Combination With Cabozantinib in Patients With Localized Clear Cell Renal Cancer.
Latest Information Update: 13 Jul 2026
At a glance
- Drugs Cabozantinib (Primary) ; Dendritic cell vaccines (Primary)
- Indications Renal cell carcinoma
- Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
Most Recent Events
- 07 Jul 2026 Planned End Date changed from 1 Dec 2026 to 1 Dec 2027.
- 07 Jul 2026 Planned primary completion date changed from 1 Dec 2026 to 1 Dec 2027.
- 04 May 2025 Trial amended with primary endpoint Reduction in tumor vascularity.