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Phase 1 Trial With GD2-SADA:177Lu-DOTA Drug Complex in Patients With Recurrent or Refractory Metastatic Solid Tumors Known to Express GD2, Including Small Cell Lung Cancer, High Risk Neuroblastoma, Sarcoma and Malignant Melanoma

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Trial Profile

Phase 1 Trial With GD2-SADA:177Lu-DOTA Drug Complex in Patients With Recurrent or Refractory Metastatic Solid Tumors Known to Express GD2, Including Small Cell Lung Cancer, High Risk Neuroblastoma, Sarcoma and Malignant Melanoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Jan 2025

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At a glance

  • Drugs GD2-SADA (Primary) ; Lutetium-(177Lu)-oxodotreotide (Primary)
  • Indications Malignant melanoma; Neuroblastoma; Sarcoma; Small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Acronyms SADA Y-PRIT
  • Sponsors Y-mAbs Therapeutics

    • Most Recent Events

    • 10 Jan 2025 Results presented in a Y-mAbs Therapeutics Media Release
    • 10 Jan 2025 According to a Y-mAbs Therapeutics Media Release, company has dosed 21 patients at six sites to date in Part A of the GD2-SADA Phase 1 trial in adults with solid tumors.
    • 10 Jan 2025 According to a Y-mAbs Therapeutics Media Release, Company Expect to present updates with respect to reprioritized SADA PRIT pipeline, including new high-value target indications and timelines, in the second quarter of 2025

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