Trial Profile

Phase 2, Single Arm, Historically Controlled Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 31 Oct 2025

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At a glance

28 Oct 2025 Planned End Date changed from 1 Sep 2025 to 1 Dec 2025.
04 Jul 2024 Planned End Date changed from 1 May 2024 to 1 Sep 2025.
10 Nov 2023 According to a Novocure Limited media release, data from the study will be presented at the 2023 Society for Neuro-Oncology (SNO) Annual Meeting from Nov. 16 to Nov. 19 in Vancouver, Canada.

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