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A Randomized, Open-Label, Eculizumab and Ravulizumab Controlled Study to Evaluate the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Currently Treated With Eculizumab or Ravulizumab

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Trial Profile

A Randomized, Open-Label, Eculizumab and Ravulizumab Controlled Study to Evaluate the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Currently Treated With Eculizumab or Ravulizumab

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs Cemdisiran (Primary) ; Eculizumab (Primary) ; Pozelimab (Primary) ; Pozelimab (Primary) ; Ravulizumab (Primary)
  • Indications Paroxysmal nocturnal haemoglobinuria
  • Focus Registrational; Therapeutic Use
  • Acronyms ACCESS 2
  • Sponsors Regeneron Pharmaceuticals

    • Most Recent Events

    • 13 Jan 2024 This trial has been Completed in Germany, according to European Clinical Trials Database record.
    • 14 Aug 2023 Status changed from active, no longer recruiting to discontinued.
    • 13 Aug 2023 This trial has been discontinued in Italy (Global end date: 20 Dec 2022).

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