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A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD

Trial Profile

A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Apr 2026

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At a glance

  • Drugs Vorolanib (Primary) ; Aflibercept
  • Indications Wet age-related macular degeneration
  • Focus Therapeutic Use
  • Acronyms DAVIO 2
  • Sponsors EyePoint; EyePoint Pharmaceuticals

Most Recent Events

  • 04 Mar 2026 According to an EyePoint Pharmaceuticals media release, the company presented DAVIO 2 trial in wet AMD data and VERONA trial in DME data at the 49th Annual Macula Society Meeting.
  • 02 Oct 2025 Actual primary completion date changed from 7 Nov 2023 to 29 Nov 2023.
  • 09 Jul 2025 According to an EyePoint Pharmaceuticals media release, results from this study presented at the 2025 Association for Research in Vision and Ophthalmology (ARVO) conference in Salt Lake City, Utah.

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