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A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD

Trial Profile

A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Vorolanib (Primary) ; Aflibercept
  • Indications Wet age-related macular degeneration
  • Focus Therapeutic Use
  • Acronyms DAVIO 2
  • Sponsors EyePoint Pharmaceuticals

Most Recent Events

  • 05 Mar 2025 According to an EyePoint Pharmaceuticals media release, end-of-trial results of this trial presented at Angiogenesis Exudation, and Degeneration 2025 in February.
  • 05 Mar 2025 According to an EyePoint Pharmaceuticals media release, 12 month data at the Hawaiian Eye & Retina annual meeting in January.
  • 04 Dec 2024 According to an EyePoint Pharmaceuticals media release, the data from the DAVIO 2 clinical trial supported the advancement of the wet AMD program and the initiation of the global Phase 3 clinical trials, LUGANO and LUCIA.

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