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A Randomized Study of Paclitaxel – Carboplatin followed by maintenance Niraparib compared to Paclitaxel – Carboplatin – Bevacizumab followed by maintenance Niraparib + Bevacizumab in Patients With Advanced Ovarian Cancer Following a Front-Line Complete Cytoreductive Surgery

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A Randomized Study of Paclitaxel – Carboplatin followed by maintenance Niraparib compared to Paclitaxel – Carboplatin – Bevacizumab followed by maintenance Niraparib + Bevacizumab in Patients With Advanced Ovarian Cancer Following a Front-Line Complete Cytoreductive Surgery

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 27 Jun 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Carboplatin (Primary) ; Niraparib (Primary) ; Paclitaxel (Primary)
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use
  • Acronyms NIRVANA-1
  • Sponsors ARCAGY/GINECO Group

    • Most Recent Events

    • 29 Jan 2024 Planned End Date changed from 1 Jan 2029 to 1 Feb 2030.
    • 29 Jan 2024 Planned primary completion date changed from 1 Jan 2024 to 1 Feb 2030.
    • 13 Sep 2022 Trial design presented at the 47th European Society for Medical Oncology Congress.

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