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Open-Label Adaptive Design Study to Explore the Safety and Efficacy of Multiple Treatment Regimens With the Akt Inhibitor SM-020 Gel in 1.0% and 0.1% Gel Formulations in Subjects With Seborrheic Keratosis

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Trial Profile

Open-Label Adaptive Design Study to Explore the Safety and Efficacy of Multiple Treatment Regimens With the Akt Inhibitor SM-020 Gel in 1.0% and 0.1% Gel Formulations in Subjects With Seborrheic Keratosis

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Oct 2023

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At a glance

  • Drugs SM-020 (Primary)
  • Indications Seborrhoeic keratosis
  • Focus First in man; Proof of concept; Therapeutic Use
  • Sponsors DermBiont
  • Most Recent Events

    • 24 Oct 2023 According to a DermBiont media release, the company announced a $35.2 million Series B financing proceeds from which will be used to advance the clinical development of SM-020 and SM-030. They are expected to fund the company through end of its Phase 2 meetings with the U.S. Food and Drug Administration (FDA), which are expected in the second half of 2024 for both programs.
    • 29 Sep 2023 Planned End Date changed from 15 Jun 2023 to 31 Jul 2024.
    • 29 Sep 2023 Planned primary completion date changed from 31 Dec 2022 to 31 May 2024.

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