Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)
Latest Information Update: 18 Feb 2025
At a glance
- Drugs SVN53-67-M57-KLH peptide vaccine (Primary) ; Temozolomide
- Indications Glioblastoma
- Focus Therapeutic Use
- Acronyms SURVIVE
- Sponsors MimiVax
Most Recent Events
- 12 Feb 2025 According to a MimiVax media release, based on the results of the recent interim futility analysis, and ongoing review by the study's Independent Data Safety Monitoring Committee, the SURVIVE trial will continue as designed without modification. the company will provide updates at appropriate milestones, in accordance with regulatory requirements.
- 12 Feb 2025 According to a MimiVax media release, the trial has successfully progressed following the first interim analysis of trial data. While the company is unable to disclose specific details about the interim analysis due to regulatory requirements set forth by the U.S. Food and Drug Administration (FDA), MimiVax remains confident in the potential of SurVaxM and is committed to advancing the study as planned.
- 04 Jun 2024 Trial design (as of Jan 2024; n=205) presented at the 60th Annual Meeting of the American Society of Clinical Oncology.