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Effects of Combination Medical Therapy Followed by Balloon Pulmonary Angioplasty on Right Ventricular-PA Coupling and Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension

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Trial Profile

Effects of Combination Medical Therapy Followed by Balloon Pulmonary Angioplasty on Right Ventricular-PA Coupling and Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 07 Sep 2026

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At a glance

  • Drugs Macitentan (Primary) ; Riociguat (Primary)
  • Indications Pulmonary hypertension
  • Focus Therapeutic Use
  • Acronyms EPIPHANY

Most Recent Events

  • 03 Sep 2026 Status changed from recruiting to discontinued.
  • 25 Feb 2025 Status changed from not yet recruiting to recruiting.
  • 18 Nov 2024 Planned End Date changed from 31 Dec 2024 to 31 Dec 2026.

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