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A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) to Determine the Feasibility and Safety of Intratumoral Injection With or Without Intramural Injection in Subjects With Bladder Cancer

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Trial Profile

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) to Determine the Feasibility and Safety of Intratumoral Injection With or Without Intramural Injection in Subjects With Bladder Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 21 Oct 2024

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At a glance

  • Drugs Belzupacap sarotalocan (Primary)
  • Indications Bladder cancer; Urogenital cancer
  • Focus Adverse reactions
  • Sponsors Aura Biosciences

    • Most Recent Events

    • 17 Oct 2024 According to an Aura Biosciences media release, company will host a Virtual Urologic Oncology Investor Event featuring Max Kates, MD (Johns Hopkins), Joe Jacob, MD (Syracuse University), Neal Shore, MD (Carolina Urologic Research Center) and Gary Steinberg, MD (RUSH University) to discuss the early Phase 1 data on Thursday, October 17, 2024, at 4:30 pm Eastern Time.
    • 17 Oct 2024 Results presented in an Aura Biosciences media release.
    • 09 May 2024 According to an Aura Biosciences media release, preliminary data from the first patient in the light activated cohort of the trial demonstrated a clinical complete response demonstrated by absence of cancer cells on histopathology with evidence of extensive necrosis and immune activation after a single administration of bel-sar followed by light activation.

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