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A Phase 1/2, Randomized, Double-blind, Placebo-controlled, Single Ascending and Multiple Dose Study of the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALN-XDH in Healthy Adult Subjects and Adult Patients With Gout

Trial Profile

A Phase 1/2, Randomized, Double-blind, Placebo-controlled, Single Ascending and Multiple Dose Study of the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALN-XDH in Healthy Adult Subjects and Adult Patients With Gout

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 01 Apr 2024

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At a glance

  • Drugs ALN-XDH (Primary)
  • Indications Gout
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Alnylam Pharmaceuticals

Most Recent Events

  • 21 Mar 2023 Status changed from recruiting to discontinued.
  • 28 Jul 2022 According to an Alnylam Pharmaceuticals media release, the company expects to report preliminary results from the study in mid or late 2022.
  • 08 Mar 2022 Status changed from not yet recruiting to recruiting.

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