Trial Profile

A Phase 2a, Randomized, Open-Label Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered to Patients With Phlebotomy Dependent Polycythemia Vera (PD-PV)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 16 Dec 2025

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At a glance

06 Dec 2025 Primary endpoint has been met. (Change in the frequency of phlebotomy comparing Baseline with the last 20 weeks of the 37 week Treatment Period)
06 Dec 2025 According to an Deciphera Pharmaceuticals media release, company announced the oral presentation of positive results from the Phase 2a IMPRSSION study of sapablursen in patients with polycythemia vera (PV) at the 67th American Society of Hematology (ASH) Annual Meeting, taking place December 6-9, 2025, in Orlando, FL.
06 Dec 2025 Results published in the Media Release

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