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LuCa-MERIT-1: First-in-human, Open Label, Phase I Dose Confirmation Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

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Trial Profile

LuCa-MERIT-1: First-in-human, Open Label, Phase I Dose Confirmation Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs BNT 116 (Primary) ; Carboplatin (Primary) ; Cemiplimab (Primary) ; Docetaxel (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; First in man
  • Acronyms LuCa-MERIT-1
  • Sponsors BioNTech

    • Most Recent Events

    • 10 Oct 2024 Planned End Date changed from 1 Aug 2027 to 1 Nov 2028.
    • 10 Oct 2024 Planned primary completion date changed from 1 Jan 2026 to 1 Apr 2027.
    • 11 Mar 2024 According to a BioNTech media release, preliminary results of this study will be presented at the American Association for Cancer Research Annual Meeting 2024 in San Diego, California, from April 5-10, 2024

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