LuCa-MERIT-1: First-in-human, Open Label, Phase I Dose Confirmation Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
Latest Information Update: 07 Jun 2025
At a glance
- Drugs BNT 116 (Primary) ; Carboplatin (Primary) ; Cemiplimab (Primary) ; Docetaxel (Primary)
- Indications Non-small cell lung cancer
- Focus Adverse reactions; First in man
- Acronyms LuCa-MERIT-1
- Sponsors BioNTech
Most Recent Events
- 07 May 2025 Protocol amended vwith addition of cohort 8 and 9
- 07 May 2025 Planned number of patients changed from 130 to 220.
- 07 May 2025 Planned End Date changed from 1 Nov 2028 to 1 Nov 2031.