A Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES-SCLC) in Combination With Carboplatin, Etoposide and Tislelizumab in Induction and With Tislelizumab in Maintenance Treatment Phase
Latest Information Update: 30 Oct 2024
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At a glance
- Drugs Atezolizumab (Primary) ; Carboplatin (Primary) ; Etoposide (Primary) ; Gallium 68-DOTATATE (Primary) ; Lutetium-(177Lu)-oxodotreotide (Primary) ; Tislelizumab (Primary)
- Indications Small cell lung cancer
- Focus Adverse reactions; Therapeutic Use
- Sponsors Novartis Pharma A.G.; Novartis Pharmaceuticals
- 04 Sep 2024 Planned End Date changed from 3 May 2028 to 1 Jun 2029.
- 04 Sep 2024 Planned primary completion date changed from 5 May 2025 to 1 Jun 2029.
- 10 Apr 2024 Phase has been changed to 1b\2,no.of arms has been increased to 8,addition of Atezolizumab 1200 mg to the treatment.