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Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation: a Multi-center, Randomized, Double-blind, Placebo-controlled Investigational Study (PAIR-TAVI)

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Trial Profile

Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation: a Multi-center, Randomized, Double-blind, Placebo-controlled Investigational Study (PAIR-TAVI)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 29 Apr 2026

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At a glance

  • Drugs Conestat alfa (Primary)
  • Indications Acute kidney injury
  • Focus Therapeutic Use
  • Acronyms PAIR-TAVI

Most Recent Events

  • 22 Apr 2026 Actual Primary Completion Date is 5 Jan 2026.
  • 22 Apr 2026 Status changed from recruiting to completed.
  • 12 Mar 2025 Planned End Date changed from 1 Mar 2025 to 1 Dec 2025.

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