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Phase 2 Trial of TGF-β Inhibition (OT-101) With Anti-PD-1 (Pembrolizumab) in Patients With Malignant Pleural Mesothelioma (MPM) Failing to Achieve or Maintain Response to Checkpoint Inhibition

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Trial Profile

Phase 2 Trial of TGF-β Inhibition (OT-101) With Anti-PD-1 (Pembrolizumab) in Patients With Malignant Pleural Mesothelioma (MPM) Failing to Achieve or Maintain Response to Checkpoint Inhibition

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Mar 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Trabedersen (Primary)
  • Indications Malignant-mesothelioma
  • Focus Therapeutic Use
  • Acronyms M201
  • Sponsors Oncotelic Therapeutics

    • Most Recent Events

    • 13 Mar 2024 Planned End Date changed from 1 Dec 2026 to 1 Dec 2029.
    • 13 Mar 2024 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2028.
    • 03 Jan 2023 Planned initiation date changed from 1 Dec 2022 to 1 Jun 2023.

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