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Randomized Phase I Study of the Infectivity, Safety, and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Infants and Children 6 to 24 Months of Age

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Trial Profile

Randomized Phase I Study of the Infectivity, Safety, and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Infants and Children 6 to 24 Months of Age

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 08 Aug 2022

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At a glance

  • Drugs RSV 276 (Primary) ; RSV/deltaNS2/delta1313/I1314L (Primary)
  • Indications Respiratory syncytial virus infections
  • Focus Adverse reactions; Pharmacodynamics
  • Most Recent Events

    • 23 Jun 2022 Pooled results from NCT03227029 and NCT0342223, published in the Journal of Infectious Diseases.
    • 09 Dec 2021 New trial record
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