Trial Profile

A Phase Ib/II Trial of JAB-21822 in Combination With Cetuximab in Patients With Advanced Colorectal Cancer, Small Intestine Cancer and Appendiceal Cancer With KRAS G12C Mutation

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 07 Apr 2026

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At a glance

Drugs Cetuximab (Primary) ; Glecirasib (Primary)
Indications Colorectal cancer
Focus Adverse reactions; Registrational; Therapeutic Use
Sponsors Allist Pharmaceuticals; Jacobio Pharmaceuticals

Most Recent Events

16 Mar 2026 Planned End Date changed from 1 Dec 2024 to 1 Dec 2026.
13 Mar 2025 Planned primary completion date changed from 1 Dec 2023 to 1 Dec 2025.
20 Aug 2024 Planned End Date changed from 1 Jan 2026 to 1 Dec 2024.

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