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A Study to Evaluate the Safety and Tolerability of the Covalent Phosphoinositide-3-Kinase (PI3K)-Alpha Inhibitor, TOS-358, in Adult Subjects With Select Solid Tumors

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Trial Profile

A Study to Evaluate the Safety and Tolerability of the Covalent Phosphoinositide-3-Kinase (PI3K)-Alpha Inhibitor, TOS-358, in Adult Subjects With Select Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Jun 2024

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At a glance

  • Drugs TOS-358 (Primary)
  • Indications Cervical cancer; Colorectal cancer; Endometrial cancer; Gastric cancer; Head and neck cancer; HER2 negative breast cancer; Non-small cell lung cancer; Ovarian cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Adverse reactions
  • Sponsors Totus Medicines

    • Most Recent Events

    • 19 Apr 2023 Trial design presented at the 114th Annual Meeting of the American Association for Cancer Research
    • 13 Apr 2023 According to a Totus Medicines media release, the first patient has been dosed in the study.
    • 10 Apr 2023 According to a Totus Medicines media release, company will be presenting poster presentation for this trial at the American Association for Cancer Research (AACR) Annual Meeting, Abstract: CT249, on Tuesday April 18 at 1:30 PM - 5:00 PM ET.full abstracts will be available on the AACR and Totus Website.
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