A Phase 1 Study of KTX-1001, an Oral, First-In-Class, Selective, and Potent MMSET Catalytic Inhibitor That Suppresses H3K36me2 in Patients With Relapsed and Refractory Multiple Myeloma
Latest Information Update: 19 Dec 2025
At a glance
- Drugs Carfilzomib (Primary) ; Dexamethasone (Primary) ; Gintemetostat (Primary) ; Mezigdomide (Primary) ; Pomalidomide (Primary)
- Indications Multiple myeloma
- Focus Adverse reactions; First in man; Proof of concept
- Sponsors K36 Therapeutics
Most Recent Events
- 05 Dec 2025 According to a K36 Therapeutics media release, results from the dose escalation part of this study will be presented at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, taking place December 6 -9, 2025, in Orlando, Florida.
- 05 Dec 2025 Results presented in the K36 Therapeutics Media Release.
- 18 Sep 2025 According to a K36 Therapeutics media release, translational data from this trial will be presented at the 22nd Annual International Myeloma Society (IMS) Meeting in Toronto, taking place September 17-20.