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A Phase 1 Study of KTX-1001, an Oral, First-In-Class, Selective, and Potent MMSET Catalytic Inhibitor That Suppresses H3K36me2 in Patients With Relapsed and Refractory Multiple Myeloma

Trial Profile

A Phase 1 Study of KTX-1001, an Oral, First-In-Class, Selective, and Potent MMSET Catalytic Inhibitor That Suppresses H3K36me2 in Patients With Relapsed and Refractory Multiple Myeloma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Feb 2026

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At a glance

Most Recent Events

  • 09 Jan 2026 Planned End Date changed from 30 Jun 2026 to 30 Jun 2028.
  • 09 Jan 2026 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2027.
  • 05 Dec 2025 According to a K36 Therapeutics media release, results from the dose escalation part of this study will be presented at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, taking place December 6 -9, 2025, in Orlando, Florida.

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