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An open label, 2-periods, fixed sequence, phase I study assessing the effect of P-glycoprotein transporter inhibition mediated by Carvedilol on the pharmacokinetics of Zamicastat in healthy volunteers

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Trial Profile

An open label, 2-periods, fixed sequence, phase I study assessing the effect of P-glycoprotein transporter inhibition mediated by Carvedilol on the pharmacokinetics of Zamicastat in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Dec 2021

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At a glance

  • Drugs Zamicastat (Primary) ; Carvedilol
  • Indications Heart failure; Pulmonary hypertension
  • Focus Pharmacokinetics

Most Recent Events

  • 24 Dec 2021 New trial record

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