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A phase II study to assess the efficacy of osimertinib in patients with EGFR mutation-positive NSCLC who developed isolated CNS progression (T790M negative or unknown) during 1st or 2nd generation EGFR-TKI or systemic disease progression (T790M negative) after treatment with 1st or 2nd generation EGFR-TKI and platinum-based chemotherapy (WJOG12819L)

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Trial Profile

A phase II study to assess the efficacy of osimertinib in patients with EGFR mutation-positive NSCLC who developed isolated CNS progression (T790M negative or unknown) during 1st or 2nd generation EGFR-TKI or systemic disease progression (T790M negative) after treatment with 1st or 2nd generation EGFR-TKI and platinum-based chemotherapy (WJOG12819L)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Oct 2023

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At a glance

  • Drugs Osimertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 12 Sep 2023 Results (n=55) assessing the Efficacy of Osimertinib , presented at the 24th World Conference on Lung Cancer
    • 15 Feb 2023 Results (n=55) published in the Lung Cancer
    • 29 Dec 2021 New trial record

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