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A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2 Proof-of-Concept Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 on Background Therapy With Conventional Synthetic Disease-modifying Antirheumatic Drug(s) (csDMARDs) in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic DMARD(s) Treatment

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A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2 Proof-of-Concept Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 on Background Therapy With Conventional Synthetic Disease-modifying Antirheumatic Drug(s) (csDMARDs) in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic DMARD(s) Treatment

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 21 May 2022

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At a glance

  • Drugs Edecesertib (Primary) ; Tofacitinib
  • Indications Rheumatoid arthritis
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 11 May 2022 Status changed from not yet recruiting to withdrawn prior to enrolment.
    • 11 Mar 2022 Planned initiation date changed from 1 Dec 2021 to 1 Jul 2022.
    • 30 Dec 2021 New trial record

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