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A Phase 1b Open-Label, Dose-Escalation, Safety, and Pharmacodynamic Study of Minnelide™ Capsules Given in Combination With Osimertinib in Patients With EGFR Mutated NSCLC

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Trial Profile

A Phase 1b Open-Label, Dose-Escalation, Safety, and Pharmacodynamic Study of Minnelide™ Capsules Given in Combination With Osimertinib in Patients With EGFR Mutated NSCLC

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Feb 2025

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At a glance

  • Drugs Minnelide (Primary) ; Osimertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions

    • Most Recent Events

    • 24 Feb 2025 Planned End Date changed from 28 Oct 2026 to 28 Oct 2027.
    • 24 Feb 2025 Planned primary completion date changed from 28 Oct 2026 to 28 Oct 2027.
    • 06 Aug 2024 Planned End Date changed from 15 Dec 2024 to 28 Oct 2026.

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